OCR General Certificate of Secondary Education (GCSE) Biology Practice Exam

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Which of the following pairs are complementary base pairs in DNA?

  1. Adenine and Cytosine

  2. Thymine and Guanine

  3. Adenine and Thymine

  4. Cytosine and Uracil

The correct answer is: Adenine and Thymine

Adenine and Thymine are known as complementary base pairs in DNA, meaning they form specific hydrogen bonds with each other. In the structure of DNA, adenine (A) pairs with thymine (T) through two hydrogen bonds, which helps maintain the double helix shape of the DNA molecule. This pairing is crucial for accurate DNA replication and transcription processes. Other base pairs that are complementary in DNA include Cytosine and Guanine, but in the options provided, only adenine and thymine specifically fit the criteria of complementary base pairs. The relationships among the bases ensure the genetic information can be reliably copied and expressed.